EXPERIMENTALLY GUIDED COMPUTATIONAL ANTIBODY AFFINITY MATURATION WITH DE NOVO DOCKING, MODELLING AND RATIONAL DESIGN.

Experimentally guided computational antibody affinity maturation with de novo docking, modelling and rational design.

Antibodies are an important class of therapeutics that have significant clinical impact for the treatment of severe diseases.Computational tools to support antibody drug discovery have been developing at an increasing rate over the last decade and typically rely upon a predetermined co-crystal structure of the antibody bound to the antigen for stru

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Relationship Between General Health and Health-Related Quality of Life in Educational Hospitals' Nurses in Ahvaz

Background: Nurses face a lot of stress in their jobs, and the quality of life has a significant impact on the quality of their services.Therefore, the purpose of this study was to determine the relationship between general health and the quality of life conditions in nurses working in hospitals affiliated with Jundishapur University of Medical Sci

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A música francesa reconfigurada no jazz modal de Bill Evans

Embora seja senso comum que a música francesa, especialmente a do século XX, tenha exercido influência no estilo improvisatório do pianista de jazz norte-americano Bill Evans (1929-1980), a importância deste papel é raramente abordada em estudos bem fundamentados.Estes dois pontos - Stove Knob música francesa e Evans - oferecem uma oportunid

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